Pipeline

       

                    We have migrated to local ESMFold inference. SPASE can handle a maximum of ~500 residues. 
                    SPASE runs will fail for structures >500 residues. 
                    We are working on upgrades to accommodate larger systems.

Run name:

Input PDB file:

Email address:

Residue selection (optional):

Please ensure you know exactly which residues to conserve. This is very specific to your pdb file as residue numbering is not always consistent. Before submitting your file to the server, please use the following tool to correctly identify which residue numbers to put in the box. Residues to conserve should be provided as a list of residue numbers separated by commas without spaces (for example: 25,37,118)

Residue selection tool

Advanced options (coming soon)

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Results will be automatically sent to your email once completed.
Depending on the size of the target, runs can take several hours to finish.